Stem Cell Biology

Wenbin Deng, University of California, Davis
This Series is interested in covering the fundamental mechanisms of stem cell pluripotency and differentiation, and strategies for translating fundamental developmental insights into the discovery of new therapies. The emphasis is on the roles and potential advantages of stem cells in developing, sustaining and restoring tissue after injury or disease. Some of the topics covered include: the signaling mechanisms of development and disease; the fundamentals of stem cell growth and differentiation; the utilities of adult (somatic) stem cells, induced pluripotent stem (iPS) cells and human embryonic stem (ES) cells for disease modeling and drug discovery; and finally, the prospects for applying the unique aspects of stem cells for regenerative medicine. We hope this Series will provide the most accessible and current discussions of the key points and concepts in the field, and that students and researchers all over the world will find these in-depth reviews to be useful.

Series ISSNs: 2168-3980 (electronic) and 2168-3972 (print)

Editor Bios

Emerging Roles for Hippocampal Adult Neural Stem Cells in Memory Emerging Roles for Hippocampal Adult Neural Stem Cells in Memory
Aaron Friedman, Daniela Kaufer
Approximately 50 years ago, newly generated neurons were discovered in the adult hippocampus of the rat brain. This discovery contradicted a key principle in mammalian developmental neurobiology-that all the neurons of the brain are made during early...
Publication Date: 12/01/2013

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Patenting Stem Cell Technologies Patenting Stem Cell Technologies
Antoinette Konski
Are stem cells patentable? What is the patenting process? What rights does a patent provide? Why should I patent? Applying for and obtaining a patent is a process that can be unpredictable and intimidating, although it does not necessarily need to be...
Publication Date: 03/01/2013

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Stem Cells and Progenitors in the Developing Liver Stem Cells and Progenitors in the Developing Liver
Marcus Muench
The human liver is a dynamic organ throughout life, but no more so than during prenatal development. The liver performs many essential functions associated with metabolism, immunity and blood production. These diverse functions are performed by a var...
Publication Date: 12/01/2012

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Stem Cells and Extracellular Matrices Stem Cells and Extracellular Matrices
Lakshmi Kiran Chelluri
Stem cells have great potential in regenerative medicine and tissue injury. Regulation of stem cell homeostasis in a 3D microenvironment is controlled by the niche components that influence stem cell fate, regulation, and function. It is therefore ne...
Publication Date: 03/01/2012

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Biobanking in the Stem Cell Era Biobanking in the Stem Cell Era
Jennifer C. Moore, Michael H. Sheldon, Ronald P. Hart
The study of mental health disorders and the genetics behind these disorders can be greatly enhanced by the use of induced pluripotent stem cells (iPSC). Since many mental health disorders develop after puberty, the only way in which to study the gen...
Publication Date: 06/01/2012

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