Neuropeptides

SERIES EDITORS:
Lakshmi Devi, Mount Sinai School of Medicine
Lloyd D. Fricker, Albert Einstein College of Medicine
Communication between cells is essential in all multicellular organisms, and even in many unicellular organisms. A variety of molecules are used for cell-cell signaling, including small molecules, proteins, and peptides. The term ‘neuropeptide’ refers specifically to peptides that function as neurotransmitters, and includes some peptides that also function in the endocrine system as peptide hormones. Neuropeptides represent the largest group of neurotransmitters, with hundreds of biologically active peptides and dozens of neuropeptide receptors known in mammalian systems, and many more peptides and receptors identified in invertebrate systems. In addition, a large number of peptides have been identified but not yet characterized in terms of function. The known functions of neuropeptides include a variety of physiological and behavioral processes such as feeding and body weight regulation, reproduction, anxiety, depression, pain, reward pathways, social behavior, and memory. This series will present the various neuropeptide systems and other aspects of neuropeptides (such as peptide biosynthesis), with individual volumes contributed by experts in the field.

Print ISSN: 2166-6628 / E-ISSN: 2166-6636

Editor Bios


Biologically Active Peptides in Invertebrates Biologically Active Peptides in Invertebrates
Qing Yu, Zhidan Liang, Chuanzi OuYang, Lingjun Li
Animal behaviors and emotions are fine-tuned via signal transmission and communication between cells. The nervous system gives instructions and transmits signals to different parts of an organism to produce coordinated activities. Neurons are core co...
Publication Date: September, 2015

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Neuropeptide Receptors Neuropeptide Receptors
Ivone Gomes, Jonathan Wardman, Steve Stockton, Lakshmi A. Devi
Neuropeptides mediate their effects by binding and activating receptors that are responsible for converting these extracellular stimuli into intracellular responses. Most neuropeptides interact with G protein-coupled receptors that transduce the sign...
Publication Date: 05/01/2013

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Neuropeptides and Other Bioactive Peptides Neuropeptides and Other Bioactive Peptides
Lloyd D. Fricker
Neuropeptides and peptide hormones represent the largest class of chemical messengers that transmit information from one cell to another. In this review, several decades of research on peptides in cell-cell signaling are summarized, with a focus on n...
Publication Date: 06/01/2012

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Bioactive Peptides Produced by Limited Proteolysis Bioactive Peptides Produced by Limited Proteolysis
Antonio C. M. Camargo, Beatriz L. Fernandes, Lilian Cruz
Proteins are considered supremely important for the organization, survival, and functioning of living organisms. They were considered stable and static molecules until the early 1940s, when RudolphSchoenheimer demonstrated that proteins exist in a co...
Publication Date: 03/01/2012

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Peptide Biosynthesis Peptide Biosynthesis
Akina Hoshino, Iris Lindberg
The prohormone convertases (PC) 1/3 and 2 are calcium-activated eukaryotic subtilisins with low pH optima which accomplish the limited proteolysis of peptide hormone precursors within neurons and endocrine cells. In this lecture, we review the bioche...
Publication Date: 01/01/2012

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