Developmental Biology

SERIES EDITORS
Daniel S. Kessler, University of Pennsylvania School of Medicine
Jean-Pierre Saint-Jeannet, New York University
Developmental biology is in a period of extraordinary discovery and research. This field will have a broad impact on the biomedical sciences in the coming decades. Developmental Biology is interdisciplinary and involves the application of techniques and concepts from genetics, molecular biology, biochemistry, cell biology, and embryology to attack and understand complex developmental mechanisms in plants and animals, from fertilization to aging. Many of the same genes that regulate developmental processes underlie human regulatory gene disorders such as cancer and serve as the genetic basis of common human birth defects. An understanding of fundamental mechanisms of development is providing a basis for the design of gene and cellular therapies for the treatment of many human diseases. Of particular interest is the identification and study of stem cell populations, both natural and induced, which is opening new avenues of research in development, disease, and regenerative medicine. This eBook series is dedicated to providing mechanistic and conceptual insight into the broad field of Developmental Biology. Each eBook is intended to be of value to students, scientists and clinicians in the biomedical sciences.

Print ISSN: 2155-3521 / E-ISSN: 2155-353X

Editor Bios


Developmental Genetics of the Pharyngeal Arch System Developmental Genetics of the Pharyngeal Arch System
Jeffry M. Cesario, Andre Landin Malt, Juhee Jeong
The pharyngeal arches are embryonic structures that develop into the face, neck, a part of the heart, and several endocrine glands in animals. They are thought to have played a key role in vertebrate evolution as their derivatives impact the mode of ...
Publication Date: May, 2015

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Wnt/β-Catenin Signaling in Vertebrate Posterior Neural Development Wnt/β-Catenin Signaling in Vertebrate Posterior Neural Development
Yaniv M. Elkouby, Dale Frank
Wnt/β-Catenin signaling pathway is a key regulator of cell fate specification, differentiation, and growth in multiple systems throughout the animal kingdom. In vertebrate posterior neural development, Wnt/β-Catenin signaling controls this complex ...
Publication Date: 01/01/2010

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Transcriptional Control of Neural Crest Development Transcriptional Control of Neural Crest Development
Brian Nelms, Patricia Labosky
The neural crest is a remarkable embryonic population of cells found only in vertebrates and has the potential to give rise to many different cell types contributing throughout the body. These derivatives range from the mesenchymal bone and cartilage...
Publication Date: 01/01/2010

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Maternal Control of Development in Vertebrates Maternal Control of Development in Vertebrates
Florence Marlow
Eggs of all animals contain mRNAs and proteins that are supplied to or deposited in the egg as it develops during oogenesis. These maternal gene products regulate all aspects of oocyte development, and an embryo fully relies on these maternal gene pr...
Publication Date: 01/01/2010

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Induction and Segregation of the Vertebrate Cranial Placodes Induction and Segregation of the Vertebrate Cranial Placodes
Byung-Yong Park, Jean-Pierre Saint-Jeannet
During evolution the vertebrate head has acquired a number of unique features including specialized paired sense organs and cranial sensory ganglia. These evolutionary novelties arise from discrete thickenings of the head ectoderm known as cranial pl...
Publication Date: 01/01/2010

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FGF Signalling in Vertebrate Development FGF Signalling in Vertebrate Development
Mary Elizabeth Pownall, Harry Isaacs
The fibroblast growth factors (FGFs) represent one of the relatively few families of extracellular signalling peptides that have been shown in recent decades to be key regulators of metazoan development. FGFs are required for multiple processes in bo...
Publication Date: 01/01/2010

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