Polycystic Kidney Disease Cristian Riella, Peter G. Czarnecki, Theodore I. Steinman This book reviews important aspects of polycystic kidney diseases, the latest scientific understanding of the diseases and syndromes, along with the therapies being developed. Cystic kidney diseases comprise a spectrum of genetic syndromes defined by... Publication Date: January, 2017
The Blood-Brain Barrier in Health and Disease William G. Mayhan, Denise M. Arrick The blood-brain barrier (BBB) is a complex and dynamic structure that protects the brain from cells within the vasculature, from the immune system and from pathogens. This barrier is present in arterioles, capillaries and venules and is formed at the... Publication Date: December, 2016
The Biliary System, 2nd Edition David Q.-H. Wang, Brent A. Neuschwander-Tetri, Piero Portincasa The biliary system is a complex network of microscopic and macroscopic structures involved in the formation of bile, an aqueous fluid in which a considerable amount of otherwise immiscible cholesterol is transported by other lipids such as bile acids... Publication Date: December, 2016
Cardiovascular Responses to Exercise, Second Edition Lusha Xiang, Robert L. Hester Exercise is the act of increasing metabolic rate for the purpose of enhancing physical fitness. Exercise can be one of the most stressful physiological responses that the body undertakes. With exercise, there are increases in metabolic rate, heart ra... Publication Date: December, 2016
Regulation of Gastrointestinal Mucosal Growth, Second Edition Rao N. Jaladanki, Jian-Ying Wang The mammalian gastrointestinal mucosa is a rapidly self-renewing tissue in the body, and its homeostasis is preserved through the strict regulation of epithelial cell proliferation, growth arrest, and apoptosis. The control of the growth of gastroint... Publication Date: November, 2016
Molecular Mechanisms of Body Water Homeostasis Carolyn M. Ecelbarger, Dharmendra Kumar Chaudhary, Hwal Lee, Swasti Tiwari This book discusses our intimate relationship with and dependence on water, how the body regulates its water levels, and various pathophysiological states associated with impairments in body water homeostasis. The human body consists of 70-80% water.... Publication Date: November, 2016
NG2-Glia (Polydendrocytes) Arthur M. Butt Classically, the central nervous system (CNS) was considered to contain neurons and three main types of glial cells - astrocytes, oligodendrocytes, and microglia. Now, it has been clearly established that NG2-glia are a fourth glial cell type that ar... Publication Date: October, 2016
Vascular Smooth Muscle Function in Hypertension Theodora Szasz, Rita C.A. Tostes Hypertension is defined by an increase in systemic blood pressure above limits considered normal, currently set at 140 mmHg for systolic and 90 mmHg for diastolic pressure. Assuming central venous pressure to be near zero, mean arterial pressure is d... Publication Date: October, 2016
X & Y Chromosomal Variations Carole A. Samango-Sprouse, Andrea L. Gropman This is the first book on X and Y chromosomal disorders to address these common but rarely diagnosed conditions. This book seeks to present the latest in research and clinical care addressing neuroimaging, the interaction between hormones, brain deve...
Regulation of Tissue Oxygenation, Second Edition Roland Pittman This book describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory ... Publication Date: August, 2016
Molecular Genetics of Thalassemia Syndromes Reena Das, Prashant Sharma This book reviews the molecular genetics of the thalassemia syndromes, inherited hemoglobin disorders that comprise the commonest monogenic disorders globally. Thalassemias are found in high frequencies in tropical regions corresponding to the malari... Publication Date: August, 2016
The Cerebral Circulation, Second Edition Marilyn J. Cipolla This book reviews special features of the cerebral circulation and how they contribute to the physiology of the brain. It describes structural and functional properties of the cerebral circulation that are unique to the brain, an organ with high meta... Publication Date: July, 2016
Adolescent Brain Development Lisa Wright, Stan Kutcher This book is the foundation of unlocking one of the greatest mysteries mankind has faced throughout history...the teen brain. The teen brain is fundamentally different from the brain of an adult or of a child, so this book provides a starting point ... Publication Date: April, 2016
Molecular Basis of Development Anomalies of the Human Gastrointestinal Tract Charles Shaw-Smith Current knowledge of the etiology of congenital malformations of the human gastrointestinal tract is covered in this book, prefaced by some introductory notes on embryological development. Malformations involving the esophagus, stomach, small and lar... Publication Date: December 11, 2015
Science and Ethics in Dialogue Ann Boyd This is a path through the potential phases and avenues of a scientific career, imagining that a person may do basic research, serve on ethics committees, and engage the public in ethical use of new advances in genetics. As a result the content of th... Publication Date: October, 2015
Biologically Active Peptides in Invertebrates Qing Yu, Zhidan Liang, Chuanzi OuYang, Lingjun Li Animal behaviors and emotions are fine-tuned via signal transmission and communication between cells. The nervous system gives instructions and transmits signals to different parts of an organism to produce coordinated activities. Neurons are core co... Publication Date: September, 2015
Lung Endothelium Mary I. Townsley, Troy Stevens Pulmonary endothelium forms the inner lining of blood vessels, where it interprets the complex mechanical and chemical environment within the circulation and adjusts its behavior to facilitate vascular homeostasis. Although endothelium fulfills many ... Publication Date: September, 2015
Measuring Cell Mechanics Margaret Gardel, Patrick Oakes Cells are inherently physical entities that both experience mechanical forces from their external environment and generate their own internal forces to drive cell motion. Our particular aim here is to present the reader with an introduction to the pr... Publication Date: September, 2015
Renal Medullary Circulation Allen W. Cowley, Jr., Louise C. Evans The two kidneys of mammalian organisms receive around 25% of the cardiac output at rest, of which only ~7% is distributed to the renal medulla. Despite the low blood flow to the renal medulla, small changes in perfusion to the region can have profoun... Publication Date: August, 2015
Genetics of Hypertension Xi Cheng, Bina Joe Hypertension, or elevated blood pressure, is a major risk factor for various cardiovascular, renal diseases, and stroke. The form of hypertension with no identifiable cause is referred to as Essential Hypertension. Familial studies indicate that Esse... Publication Date: August, 2015
Linking the World's Information When Sir Tim Berners-Lee first proposed the foundations of the World Wide Web at CERN in 1989, his manager called it “vague, but exciting...